Hypochlorous acid is a reliable solution for fighting enveloped viruses like COVID-19. Social media trends have also encouraged its use in dermatology, treating skin conditions like acne.i
For dental practices, hypochlorous acid is good for infection control but its effectiveness is dependent on diligent management and compliance. So how suitable is it?
Hypochlorous acid is naturally created in the body, when white blood cells attack invading pathogens and produce the acid in response to injury and infection.ii Its pH range is 3–6 for aqueous solutions, with 3.5–5 considered a stable form that optimises antimicrobial activities.ii
Electrolysis creates hypochlorous acid from a combination of water, non-iodised salt and vinegar. This can be achieved in 8 minutes, with a safer pH of 5–6.5 that is ready to use for disinfection against a broad range of microorganisms.iii For healthcare providers, hypochlorous acid can be used for wound care, hand hygiene, surface application and, of note to dental professionals, to target biofilm, especially in the dental unit water lines (DUWLs).
However, hypochlorous acid solutions that fail to meet compliance standards can increase the risk of pathogen transmission and damage the equipment in the dental practice.
This means using properly formulated solutions at the recommended pH level to avoid:
Hypochlorous acid must meet biocide compliance standards. Depending on claims and specific intended purpose, this could be adhering to the GB BPR and/or the MDR / MDD (CE UKCA). This can be particularly problematic and ambiguous with in-practice generator systems.
To further reduce the risk of damage to the dental practices, hypochlorous acid must be stored in a safe and stable manner. This is because the solution is highly reactive, in turn impacting its concentration and therefore its functionality. The following steps are required:
Failure to meet the regulations and storage guidelines for hypochlorous acid can have a detrimental impact on the dental practice as its antimicrobial qualities are diminished. For instance, in DUWLs, if the water quality is not checked and maintained to the CQC standard, biofilm can coat the plastic material and disperse microorganisms through the water network. This will eventually pose a risk to patients and dental team.iv
Another drawback is that any errors in measurements causes delays in time and product waste (especially when considering that the antimicrobial activity of the solution is dependent on the optimal pH).v Some formulations may require a thorough rinse out of the waterlines before the end of each working day – this can be a further inconvenience and runs the risk of being overlooked.
For cleaning DUWLs and other components of the dental practice, a non-toxic and non-corrosive disinfectant and maintenance solution that is easy to store is superior to hypochlorous acid solutions. It must also be effective in various forms and relatively inexpensive.
The Dentisan product range is filled with reliable infection control solutions, including for managing DUWLs. These ensure compliance with HTM 01-05 and support a seamless integration into the daily workflow. For those unsure on the correct regulations or dental practices looking for a refresher, the Dentilearn in-practice CPD sessions are an excellent way of staying up to date on infection control compliance.
The need for correct infection control protocols means using HTM 01-05 compliant products that are properly maintained. Whilst hypochlorous acid can be beneficial, it demands considerable attention, with many margins for error and non-compliance. For the safety of patients, the dental team and the reputation of the dental practice, cleaning solutions are recommended.
Sources
i.Sweeney, E. (2026). Why Are People Obsessed With Hypochlorous Acid? [online] TIME. Available at: https://time.com/7358447/what-is-hypochlorous-acid/.
ii. Wang, L., M Bassiri, Najafi, R., Najafi, K., Yang, J., B Khosrovi, Hwong, W., Barati, E., Belisle, B., C Celeri and Robson, M. (2007). Hypochlorous Acid as a Potential Wound Care Agent: Part I. Stabilized Hypochlorous Acid: A Component of the Inorganic Armamentarium of Innate Immunity. Journal of Burns and Wounds, [online] 6, p.e5. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC1853323/.
iii. Shajahan, I., Kandaswamy, D., Srikanth, P., Narayana, Ll. and Selvarajan, R. (2016). Dental unit waterlines disinfection using hypochlorous acid-based disinfectant. Journal of Conservative Dentistry, 19(4), p.347. doi:https://doi.org/10.4103/0972-0707.186441.
iv. Shajahan, I., Kandaswamy, D., Srikanth, P., Narayana, Ll. and Selvarajan, R. (2016). Dental unit waterlines disinfection using hypochlorous acid-based disinfectant. Journal of Conservative Dentistry, 19(4), p.347. doi:https://doi.org/10.4103/0972-0707.186441.
v. Haralović, V., Mokos, M., Špoljar, S., Dolački, L., Šitum, M. and Lugović-Mihić, L. (2025). Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties. Biomedicines, [online] 13(12), p.2921. doi:https://doi.org/10.3390/biomedicines13122921.